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While studies have drawn some parallels between HGH and anabolic steroids, it has become evident that better results are achieved with HGH. Like anabolics, growth hormones cause muscle cells to enlarge, this is known as muscular hypertrophy. In addition, HGH assists in burning fat, stengthens cartilage and tendons and increases the number of muscle cells (muscular hyperplasia).These results do not disappear immediately after discontinuing treatments.
Increasing numbers of athletes all over the world, especially bodybuilders, are now receiving HGH treatments. This is mostly to the fact that it is undetectable in urine drug tests. HGH must be administered in conjunction with thyroid hormone, insulin and anabolic steroids in order to be effective. It should also be injected multiple times throughout the course of the day as it metabolizes quickly. HGH has been utilized by athletes in the United States for many years now.
Before and during the creation of the now popular synthetic HGH, athletes relied on the pituitary extracts of cadavers. Unfortunately it was discovered that there were ties between using this form of HGH and a rare and fatal brain virus called Creutzveldt Jacob disease. While it affected only a very small percentage of users, the FDA removed this version of the growth hormone from the market.
As a result of years of experiments, Genentech released the original branded HGH synthetic, Protropin . Shortly thereafter Eli Lilly introduced Humatrope. It contained a slightly different formula which utilized only 191 amino acid chains in sequence as opposed to the 192 in Protropin. Studies showed that the formula in Humatrope was more effective.
While the development of these synthetics has made great improvements in the effectiveness and safety of growth hormone treatments, it did not however, make treatment more affordable, as some expected. The cost to athletes is still approximately $2000 per month.
There are now many versions of HGH throughout Europe most of which resemble the formulation in Humatrope (191 chains). There are still countries utilizing the original formulation in Protropin. For the most part these drugs are being used to treat patients suffering from dwarfism caused by a deficiency in the pituitary gland but there are athletes out there utilizing them in the never ending quest to enhance performance.
HGH found naturally in the body is produced by the pituitary gland. The level of production is at its highest during the teen years when it is utilized to promote tissue growth and aid in the breakdown of proteins and fat for use as energy. With age a natural ebb is normal. The HGH is still being produced but the results are not the same. Those receiving external treatments are essentially looking to "turn back the clock" by reintroducing the hormone to their bodies. The result is more energy and reduction of excess fat.
Theoretically growth hormone injections work well, but opinions stating the contrary are becoming more common. Many athletes have expressed disappointment in the results achieved. Certain studies have yielded data which suggest that the synthetic is being counteracted by antibodies which are produced at commencement of treatment. Although this reaction is less common when using formulations like the ones found in Humatrope (191 amino acid sequence), consistency is still an issue.
While some speculate that the reason for this counteraction is that the body no longer responds to heightened levels of HGH, once a certain age is reached, others believe that the "less than stellar" results are being seen by people who are not receiving a high enough dosage. Some athletes choose to enhance the effects by using it in combination with anabolic steroids and have reported excellent results.
Despite reports from disappointed users, HGH is being used world wide by thousands of athletes at the top of their game. A large number of which compete in the Olympics. Like in many other competitions, the athletic committees have disallowed the use of the drug. Users are of course not deterred, mostly because it is undetectable by conventional drug tests.
Length of use varies from 6 weeks on up, as many continue until they can no longer afford it. Side effects are rare but include acromegaly, diabetes as well as other skin and joint disorders.
It appears to be only a matter of time until the sports and athletic authorities begin to ban all HGH usage as they have done with steroids.
